of no effect常用作be of no effect 而to no effect可以We tried to do sth.to no effect或者We tried to do sth.逗号but to no effect,也通常在前面加little 用法可以是little to effect on sth.
1、If policy holder cheats to obtain premium, due to the malice, the insurance contract signed will be of no effect凡是投保人出于恶意.以骗取保险金为目的订立的保险合同无效
2、We tried again and again, but to no effect.
我们试了又试,但毫无效果