The shop is opening from 8:00 a.m to 6:00pm.不对,
The shop is open from 8:00 a.m to 6:00p.m是对的.
open在这里是形容词,因此前面有be,open当然不能加ing.
如果open作动词用,那它应该是点动词,可以用进行时,但是不能与from 8:00 a.m to 6:00pm同时出现在一句话中,通常用一般现在时,The shop opens at 8:00 a.m.and closes at 6 p.m.