选A.
be in charge of 是固定搭配.意为“负责”.本句译为：约翰做家具生意,他负责这桩买卖.b,怎么错了，我查的也是负责什么be in charge of 是主动的,指对...有掌控权be in the charge of 是被动的,指被...控制/支配/管理, 如He is in charge of the island.=The island is in the charge of him