maybe you can talk about the gender inequality prevalent in our society and other countries in Africa or India,like how men are superior over women
than you can investigate the issue why some people wish to be transexual (ie man turning to woman and vice versa)
you can include the motives and reasons why they are doing so,the procedures that is required to take place,and the general opinion of the society on such people attempting to change their genders
hope that's "新颖" enough