have charge of sth 意为“have responsibility for sth 对某事物有责任”.
take charge of sth 意为“take control of sth; become responsible for sth 控制或掌管某事物;承担某事物的责任”.
have full charge of friendliness 对友谊负有全责.
take full charge of friendliness 承担友谊的全部责任.