0.125^2009*(2^2010)^3-8^100*(1/2)^300
=0.125^2009*(2^3)^2010-(2^3)^100*(1/2)^300
=0.125^2009*8^2010-2^(3*100)*(1/2)^300
=0.125^2009*8^2009*8-2^300*(1/2)^300
=(0.125*8)^2009*8-(2*1/2)^300
=1^2009*8-1^300
=8-1
=7