no matter what只能放在句首,在句中,只能用whatever .
eg：No matter what happened,he would not mind.=Whatever happened,he would not mind.
不管发生什么,他不在意.
no matter 不能引导主语从句和宾语从句.
错）No matter what you say is of no use now.（对）Whatever you say is of no use now.你现在说什么也没用了.（Whatever you say是主语从句）