不是的,有以下两种情况不要改变.
1：What's wrong(the matter) with you?
Which the way(answer) to the...
EX:What's wrong with with the little boy?(she asked)
She asked what was wrong with the little boy.
2：对助于或部分主语提问所得到的特殊疑问句.
EX:Whose mother is the best at playing the violin?(we didn't know)
We didn't know whose mother was the best at playing the violin.