①：be filled with侧重于动作和装的东西
example:
The basketball is filled with apples by the old man.
②：be full of 侧重于状态
example:
The bottle is full of water.
区别并不大,主要看你要写句字时的侧重点
full是形容词；fill是动词.
full,fill二者均与“满”有关.
full是形容词,意思是“满的”,与of组成be full of短语.
fill做动词,意思是“装满”,与with组成be filled with,表示“用……把……装满”.