talk to
1 同(某人)谈话 2 责骂
I really enjoy talking to you.
同你谈话我十分高兴.
Don't talk to strangers!
不要对陌生人讲话!
Talk to yourself.
自言自语.
talk with
v.与…交谈,想说服
Would you like to talk with Mr.Bill?
你愿意跟比尔先生谈谈吗?
I want to have a long talk with you.
我想跟你好好谈一谈.
一般时候 ,如果不是刻意区分,是可以互换的.
如果非要区别：
talk to 指的是一方对另一方,用在高一级与低一级的人说话,如“上司对下属”就用to,而talk with 是指两方的,不分主次,是平级的.