to begin with 固定用法,意思是：首先,第一点.不需要跟宾语.但是它的逻辑宾语是后面的整句话.
To begin with,we must consider the faculties of the staff all-sidedly.
首先,我们必须全面地考虑全体员工的素质.
We can't go.To begin with,it's too cold.
我们不能去.首先,天太冷了.