1.0.25-16x^ 4
=0.5^2-(4x^2)^2
=(0.25+4x^2)(0.25-4x^2)
=(0.25+4x^2)(0.5+2x)(0.5-2x)
2.（x^ 2-3)^ 2-12(x^ 2-3)+36
=(x^ 2-3-6)^2
=(x-9)^2
=(x+3)^2(x-3)^2